Transcranial Direct Current Stimulation (tDCS) and Cognitive Remediation Therapy for Psychosis

What is the tDCS study?

tDCS and Cognitive Remediation Therapy for Psychosis is a research study being conducted by Kelvin Lim, M.D. and Ian Ramsay, Ph.D. about how the combination of tDCS and web-based cognitive trainings can help people with psychosis lessen their symptoms, learn new thinking and problem-solving skills, and improve their overall quality of life.

What would happen if I decide to participate?

Research staff would interview you and complete some assessments with you about your symptoms and how you are feeling. You would also be given some computerized assessments to measure your thinking skills, some of which we would measure your brain activity with electrodes attached to your face and head. You would then be assigned by chance to one of two groups: active tDCS stimulation or sham tDCS stimulation. People in each group go through the same procedure, but do not know which group they are in. You would return 2-4 times per week for 3-4 weeks for a total of 10 tDCS sessions. After the ten sessions are completed, you would complete another round of assessments, including the symptom assessments, computerized assessments, and brain activity measurements. You would then be asked to return after one month for a shorter round of follow-up assessments.

How long will the study take?

If you decide to participate in this study, you would be actively involved in the study for approximately 4-5 weeks. You would be enrolled in the study for approximately 2-3 months.

Why participate in the tDCS study?

Although you may not directly benefit from participating in this research, the information that you provide will help health professionals understand how computerized training and tDCS could be used in the future to help people with psychosis lessen their symptoms and learn new thinking skills and problem-solving abilities. You would be paid up to $65 for completing assessments at the beginning of the study. After each of the ten tDCS training sessions, you would receive $15. After the training is complete, you would receive $50 for completing another round of assessments. Finally, you would receive $25 for completing a short round of assessments one month later. In total, you could receive up to $290 for participating in this study.

Tags: Psychosis

Study team

Principal Investigator (PI):
Co-PI(s):
Study Coordinator:

Study status

Enrolling participants

Who can participate?

Study participants should:

  • Have a diagnosis of schizophrenia or schizoaffective disorder
  • Be between the ages of 18 and 64 years old
  • Be fluent in written and spoken English
  • Be an outpatient (for at least one month)
  • Be on a stable does of psychiatric medication (for at least one month)
  • Not have a history of seizures, epilepsy, craniotomy, stroke, or eczema on the scalp
  • Not have metallic cranial plates, screws, or implanted devices
  • Not be pregnant or possibly pregnant
  • Not have pre-existing sores or lesions on scalp or forehead