Identifying Biological Signatures of N-Acetylcysteine for Non-Suicidal Self-Injury in Adolescents and Young Adults

A biological study looking at the antioxidant effects of N-acetylcysteine (NAC) in the brain of adolescent girls & young women who self-harm.

Self-harm among adolescents and young adults is a current problem and few treatments are currently available. Our previous research suggested that N-acetylcysteine (NAC), a nutritional supplement with antioxidant effects, may be helpful for self-harm. The purpose of this study is to find out how NAC works by measuring its antioxidant effects in the brain.

What will this study involve?

  • Clinical assessment

  • MRI brain scans

  • Blood samples

  • Take 3 tablets twice a day of NAC or placebo for 4 weeks

  • Online surveys once a week

  • Compensated for your time

Study team

Principal Investigator (PI):
Study Coordinator:

Study status

Enrolling participants

Who can participate?

  • Females

  • 16-24 years of age

  • Recent/current self-harm

For more information or to schedule a screening, contact study coordinator Nathan Horek at 612-626-7635 or