Ziad Nahas, MD, MSCR

Professor and Vice-Chair for Clinical Affairs, Department of Psychiatry

Professor and Vice-Chair for Clinical Affairs, Department of Psychiatry


MD, Saint Joseph University, Beirut, Lebanon

Residency, Psychiatry, Baylor College of Medicine, Houston, Texas

Fellowship, Functional Neuroimaging and Psychopharmacology, Medical University of South Carolina

MS, Clinical Research, Medical University of South Carolina

Internship, Psychiatry, L’Institut Paul Silvadon and Hopital Charles Foix in Paris France

Summary

Dr Nahas received my Medical Degree from Saint Joseph University in Lebanon. He then completed an internship in Psychiatry at L’Institut Paul Silvadon, a lacanian day-hospital, and Hopital Charles Foix, both in Paris France. He moved to Houston Texas in 1993 as a resident in Psychiatry at Baylor College of Medicine. I also attended the Houston-Galveston Psychoanalytic Institute’s psychodynamic psychotherapy course. He later joined the Medical University of South Carolina (MUSC) in 1997 where I completed a research fellowship in Functional Neuroimaging and Pyshcopharmacology and a Master of Science in Clinical Research. He was a faculty member from 1999 to 2011 with a specific focus on research in mood disorders and brain stimulation. From Summer 2011 to Spring 2017, Dr Nahas was the Chair of the Department of Psychiatry at the American University of Beirut Medical Center (AUBMC) where he helped develop the department's clinical, education and research portfolio.

In addition to his scientific and academic contributions, Dr Nahas has been a strong advocate for the parity of mental health care coverage in Lebanon. He co-founded Embrace http://www.embracefund.org, a Non Profit Organization to fight stigma associated with mental illness and provide financial support for patients who cannot afford the cost of their treatments. Embrace has launched the first Suicide Prevention Help Line in the Middle East.

Awards & Recognition

Dr Nahas has received several awards including the NARSAD Independent Investigator Award and the Developing Scholar Award at MUSC. He is a full member of the American College of Neuropsychopharmacology.

Languages

  • Arabic
  • English
  • French

Research

Research Summary/Interests

Dr Nahas scientific interests lie in translational research of mood dysregulation and depressive disorders. His unique expertise is in functional neuroimaging and brain stimulation across various modalities [Transcranial Magnetic Stimulation (TMS), Vagus Nerve Stimulation (VNS), Epidural prefrontal Cortical Stimulation (EpCS), Deep Brain Stimulation (DBS), Electroconvulsive Therapy (ECT) and Focally Electrically Administered Seizure Therapy (FEAST)]. He has also conducted basic research and collaborated on health economic studies. He received funding from various sources, notably the National Institute of Mental Health, National Alliance for Research in Schizophrenia and Depression (NARSAD) and the Hope for Depression Research Foundation (HDRF). 

Publications

  1. Nahas Z, Lomarev M, Roberts DR, Shastri A, Lorberbaum JP, Teneback C, McConnell K, Vincent DJ,Li X, George MS, Bohning DE. Unilateral Left Prefrontal Transcranial Magnetic Stimulation Produces Intensity-Dependent Bilateral Effects as Measured with Interleaved BOLD fMRI. Biological Psychiatry Biol Psychiatry. 2001 Nov 1;50(9):712-20.
  2. Nahas Z, Teneback C, Speer AM, Stallings L, Molloy M, Cheng T, Risch SC, George MS. The Effect of Frequency and Distance of TMS on Prefrontal Cortex Blood Flow. Journal of Neuropsychiatry and Clinical Neurosciences. 2001 13:459-470.
  3. Nahas Z, Kozel FA, Li X, Anderson B, George MS: A Randomized Controlled Trial of Left Prefrontal Transcranial Magnetic Stimulation Treatment of Bipolar Affective Disorder Depression. Bipolar Disord. 2003 Feb;5(1):40-7.
  4. Nahas Z, Marangell L, Hussein M, Rush JA, Sackeim HA, Lisanby SH, Martinez JM, George MS. Two Year Outcome of Vagus Nerve Stimulation (VNS) Therapy for Major Depressive Episodes. J Clin Psychiatry. 2005 Sep;66(9):1097-1104.
  5. Nahas Z, Teneback C, Chae JH, Mu Q, Molnar C, Kozel FA, Walker J, Anderson B, Koola J, Kose S, Lomarev M, Bohning DE, George MS. Serial vagus nerve stimulation functional MRI in treatment-resistant depression. Neuropsychopharmacology. 2007 Aug;32(8):1649-60.
  6. Nahas Z, Anderson B, Borckardt J, Arana A, George MS, Reeves ST, Takacs E. Bilateral epidural prefrontal cortical stimulation (EpCS) for treatment-resistant depression. Biol Psych Priority Communication 2010 Jan 15;67(2):101-9. Epub .
  7. Hajcak G, Anderson BS, Arana A, Borckardt J, Takacs I, George MS, Nahas Z, Regional specificity in emotional regulation within the prefrontal cortex: Evidence from direct epidural prefrontal cortical electrical stimulation and event-related potentials Neuroscience Neuroscience. 2010 Sep 29;170(1):281-8.
  8. Pincus, D; Kose, S; Arana, A; Johnson, K; Morgan, P, Herbsman, T; Hardaway, F; George, MS; Panksepp, J; Nahas, Z Opposite effects of intra-nasal Oxytocin on Mentalization in Depressed vs. Normal Subjects: A double-blind placebo controlled fMRI study Frontiers in Neuropsych Imaging and Stim. 2010;1(134):1-10.
  9. Nahas Z, Short B, Burns C, Archer M, Schmidt M, Prudic J, Nobler MS, Devanand DP, Fitzsimons L, Lisanby SH, Payne N, Perera T, George MS, Sackeim HA. A feasibility study of a new method for electrically producing seizures in man: focal electrically administered seizure therapy [FEAST]. Brain Stimul. 2013 May;6(3):403-8. doi: 10.1016/j.brs.2013.03.004. Epub 2013 Mar 16.
  10. Karameh, F.N., Awada, M., Mourad, F. , Zahed, K. , Abou-Faycal, I., Nahas, Z. Modeling of neuronal population activation under electroconvulsive therapy. BIOSIGNALS 2014 - 7th Int. Conference on Bio-Inspired Systems and Signal Processing, Proceedings; Part of 7th Int. Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014 2014, Pages 229-238.
  11. Sawaya H, Johnson K, Schmidt M, Arana A, Chahine G, Pincus D, George MS, Panksepp J, Nahas Z. Resting-state Functional Connectivity of Antero-medial Prefrontal Cortex Sub-regions in Major Depression and Relationship to Emotional Intelligence" Int J Neuropsychopharmacol. 2015 Mar 5;18(6).

Teaching

Academic Interests and Focus

Mood disorders; neuromodulation; empathy

Clinical

Board Certifications

  • American Board of Psychiatry and Neurology

Clinical Interests

Treatment resistant mood disorders; anxiety disorders; neuromodulation; insight oriented dynamic psychotherapy